Dialyzable Leukocyte Extract (Transfer Factor) as Adjuvant Immunotherapy in the Treatment of Cancer
نویسنده
چکیده
Dialyzable Leukocyte Extract (DLE) is an extract obtained from immune lymphocytes capable of transferring antigenspecific information for cell-mediated immunity (CMI) from an immunized donor to a naïve recipient. Those products, also called Transfer Factors (TF), are peptides of 3500-6000 kDa in molecular weight; light yellow fluid with pH 6.5-7.0, composed of oligoribonucleotides attached a peptide molecule that is inherent in all animal bodies. Due to TF has a small size it could act as an immunomodulator providing a cryophilic property. TF is thermolabile but has a high stability under cold temperatures. TF can be preserved for years between -20 °C and -70 °C.
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